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DCF valuation

What is Alnylam Pharmaceuticals, Inc. worth?

With the base-case assumptions below, a discounted cash flow model on Alnylam Pharmaceuticals, Inc.'s reported free cash flow gives $126.85 per share. The share price was $255.96 on September 25, 2026, 102% above that value.

Inputs from the filings

Free cash flow, fiscal 2025
$465.4M
Average free cash flow, last 5 years
-$173.3M
Cash
$1.71B
balance sheet of June 30, 2026
Debt
$0
not reported, counted as 0
Diluted shares, fiscal 2025
134,684,000
Revenue growth per year, last 5 years
49.8%

Three sets of assumptions

CaseGrowth yrs 1-5Growth yrs 6-10After year 10Discount rateValue per shareValue vs price
Bear10.0%6.0%2.0%10.0%$82.05-68%
Base15.0%9.0%2.5%9.0%$126.85-50%
Bull20.0%11.5%3.0%8.0%$210.26-18%

Sensitivity: base case value per share

Discount rate down the side, growth after year 10 across the top. Everything else as in the base case.

1.5%2.0%2.5%3.0%3.5%
7.0%$160.76$171.34$184.26$200.42$221.20
8.0%$135.29$142.14$150.25$159.97$171.86
9.0%$116.75$121.44$126.85$133.16$140.62
10.0%$102.69$106.03$109.80$114.12$119.11
11.0%$91.69$94.14$96.87$99.94$103.43

Where the presets come from

Base: years 1 to 5 grow at Alnylam Pharmaceuticals, Inc.'s revenue growth rate over the last 5 fiscal years (49.8% a year), held between -5% and 15%. Years 6 to 10 grow halfway between that and the long-run rate of 2.5%. Future cash is discounted at 9% a year.

Bear: 5 points less growth, 2% long-run growth, 10% discount rate. Bull: 5 points more growth (at most 25%), 3% long-run growth, 8% discount rate.

Value per share = (present value of 10 years of free cash flow + present value of everything after + cash - debt) / diluted shares.

This is a model run on assumptions, not a recommendation or a price target. Small changes in the discount rate or growth move the result a lot, as the table above shows. Change them yourself in the calculator.

Adjust the assumptions

Move the sliders for growth, long-run growth and discount rate, or switch to average free cash flow, and see the value per share change.

Adjust the assumptions

Alnylam Pharmaceuticals, Inc. company page